CD248 enhances tissue factor procoagulant function, promoting arterial and venous thrombosis in mouse models.
Piyushkumar R KapoparaNooshin S SafikhanJenny L HuangScott C MeixnerKevin GonzalezHoura LoghmaniWolfram RufAlan E MastVictor LeiEdward L G PryzdialEdward M ConwayPublished in: Journal of thrombosis and haemostasis : JTH (2021)
CD248 is a newly uncovered protein partner and potential therapeutic target in the TF-FVIIa-FX macromolecular complex that modulates coagulation.