Low visceral adipose tissue regulatory T cells are associated with higher comorbidity severity in patients undergoing bariatric surgery.
Anahita JalilvandAlecia BlaszczakDavid BradleyJoey LiuValerie WrightBradley NeedlemanWilla HsuehSabrena F NoriaPublished in: Surgical endoscopy (2020)
Within bariatric candidates, lower visceral AT-Treg abundance was associated with increased baseline medication requirements for type 2 diabetes, hypertension, and hyperlipidemia. This suggests that reduced AT-Tregs may be associated with higher obesity-related comorbidity severity.
Keyphrases
- insulin resistance
- regulatory t cells
- adipose tissue
- weight loss
- bariatric surgery
- high fat diet
- type diabetes
- high fat diet induced
- patients undergoing
- metabolic syndrome
- dendritic cells
- glycemic control
- skeletal muscle
- blood pressure
- roux en y gastric bypass
- obese patients
- gastric bypass
- healthcare
- cardiovascular disease
- antibiotic resistance genes
- emergency department
- weight gain
- physical activity
- body mass index