Metabolomics approach in the investigation of depression biomarkers in pharmacologically induced immune-related depression.

Andreas BaranyiAndreas MeinitzerHans-Bernd RothenhäuslerOmid Amouzadeh-GhadikolaiDirk V LewinskiRobert J BreiteneckerMarkus Herrmann

Published in: PloS one (2018)

The results of the present study suggest that the branched-chain amino acid isoleucine might play a role in the pathophysiology of immune-related major depression, which expands existing knowledge about inflammatory hypothesis of depression.

Keyphrases

depressive symptoms
sleep quality
amino acid
healthcare
mass spectrometry
oxidative stress
drug induced
high glucose
diabetic rats