Patient characteristics in tardive COVID-19 pseudoperniosis: a case series of 16 patients.
B GanatraR AmarnaniY AlfalloujiK DearE TwiggJ P WestwoodB GouldenV MorrisT HillmanS GoolamaliZ NaderiR SidwellP ElleryE CalonjeGeorgios KravvasChristopher Barry BunkerPublished in: Clinical and experimental dermatology (2021)
Unlike acute PP, TCPP has a protracted and delayed presentation that is typically associated with profound acrocyanosis. Patients with TCPP represent a new phenomenon that is part of the post-COVID-19 syndrome, with risk factors and pathophysiology that are not yet fully understood. Our data indicate that likely predisposing factors for developing TCPP include young age, a preceding history of cold intolerance and an arachnodactyloid phenotype. Anorexia, connective tissue disorders or sickle cell trait may also predispose to TCPP. In addition, low titre antinuclear antibody positivity, the presence of cryoglobulins, or low complement levels may represent further risk factors. Finally, prolonged low temperatures are also likely to be contributing to the symptoms.
Keyphrases
- risk factors
- coronavirus disease
- sars cov
- case report
- end stage renal disease
- ejection fraction
- newly diagnosed
- peritoneal dialysis
- prognostic factors
- gene expression
- respiratory failure
- middle aged
- dna methylation
- electronic health record
- autism spectrum disorder
- respiratory syndrome coronavirus
- deep learning
- aortic dissection
- sleep quality
- extracorporeal membrane oxygenation
- data analysis