Migraine and risk of hypertensive disorders of pregnancy: A population-based cohort study.
Holly Michelle CroweAmelia K WesselinkElizabeth E HatchLauren A WiseSusan S JickPublished in: Cephalalgia : an international journal of headache (2023)
A history of migraine prior to pregnancy was associated with an increased risk of hypertensive disorders of pregnancy (RR = 1.17, 95% CI: 1.09-1.26). The greatest risk was among those with pre-pregnancy migraine that persisted into the first trimester (RR = 1.84, 95% CI: 1.35-2.50). Use of migraine medication was associated with a higher risk of hypertensive disorders of pregnancy compared to non-migraineurs (RR = 1.50, 95% CI: 1.15-1.97). Results from this study indicate that migraine is a potential risk factor for hypertensive disorders of pregnancy.