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The Efficacy of PD-1/PD-L1 Inhibitors in Patients with Liver Metastasis of Non-Small Cell Lung Cancer: A Real-World Study.

Mingying XieNa LiXiaoling XuYanjun XuHui LiLiang ZhuJiamin ShengZi-Chao ZhouYun Fan
Published in: Cancers (2022)
PD-1/PD-L1 inhibitors are effective in liver metastasis-NSCLC patients. However, the efficacy is inferior when compared to those of patients without liver metastases. In NSCLC patients with liver metastases, PD-L1 expression and CD8+ T cell infiltration can predict the response of PD-1/PD-L1-directed immunotherapy.
Keyphrases
  • liver metastases
  • end stage renal disease
  • ejection fraction
  • newly diagnosed
  • small cell lung cancer
  • chronic kidney disease
  • peritoneal dialysis
  • advanced non small cell lung cancer