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Coronary Artery Disease in Persons With Human Immunodeficiency Virus Without Detectable Viral Replication.

Andreas Delhbaek KnudsenAndreas FuchsThomas Lars BenfieldJan GerstoftLars Valeur KøberMarius TrøseidKlaus Fuglsang KofoedSusanne Dam Nielsen
Published in: Open forum infectious diseases (2023)
In a large population of PWH without viral replication, almost half had angiographically verified atherosclerosis. High concentrations of IL-6 and hsCRP were associated with CAD in univariable analyses, but adjustment for cardiovascular risk factors attenuated the association, suggesting that inflammation may mediate the association between traditional risk factors and CAD.
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