Depth of Invasion: Influence of the Latest TNM Classification on the Prognosis of Clinical Early Stages of Oral Tongue Squamous Cell Carcinoma and Its Association with Other Histological Risk Factors.
Ignacio Navarro CuéllarSamuel Espías AlonsoFrancisco Alijo SerranoIsabel Herrera HerreraJosé Javier Zamorano LeónJosé Luis Del Castillo Pardo de VeraAna María López LópezCristina Maza MuelaGema Arenas de FrutosSantiago Ochandiano CaicoyaManuel Tousidonis RialAlba García SevillaRaúl Antúnez-CondeJosé Luis Cebrián CarreteroMaría Isabel García-Hidalgo AlonsoJosé Ignacio Salmerón EscobarMiguel Burgueño GarcíaCarlos Navarro VilaCarlos Navarro CuéllarPublished in: Cancers (2023)
Depth of invasion is a histological risk factor in early clinical stages of oral tongue squamous cell carcinoma. Depth of invasion impacts negatively on patient prognosis, is capable per se of modifying the T category and the global tumour staging, and is associated with the presence of cervical metastatic disease, perineural invasion and tumoural differentiation grade.