Association of SDF1 and MMP12 with Atherosclerosis and Inflammation: Clinical and Experimental Study.
María Marcos-JubilarJosune OrbeCarmen RoncalFlorencio J D M MachadoJosé Antonio RodriguezAlejandro Fernandez-MonteroInmaculada ColinaRaquel RodilJuan Carlos PastranaJose Antonio ParamoPublished in: Life (Basel, Switzerland) (2021)
The combination of high circulating SDF1, MMP12 and CRP identified patients with particular inflammatory cardiovascular risk and increased mortality. SDF1/CXCR4 axis and MMP12 involvement in atherosclerosis development suggests that they could be possible atherosclerotic targets.