MDR-TB treatment as prevention: The projected population-level impact of expanded treatment for multidrug-resistant tuberculosis.
Emily A KendallAndrew S AzmanFrank G CobelensDavid W DowdyPublished in: PloS one (2017)
Expansion of diagnosis and treatment of MDR-TB, even using current sub-optimal second-line regimens, is expected to significantly decrease MDR-TB incidence at the population level. Focusing MDR diagnostic efforts on previously-treated cases is an efficient first-step approach.
Keyphrases
- multidrug resistant
- mycobacterium tuberculosis
- drug resistant
- acinetobacter baumannii
- gram negative
- klebsiella pneumoniae
- climate change
- risk factors
- emergency department
- cystic fibrosis
- escherichia coli
- replacement therapy
- pulmonary tuberculosis
- pseudomonas aeruginosa
- human immunodeficiency virus
- smoking cessation
- hiv infected
- newly diagnosed