Chronic adult-onset of growth hormone/IGF-I hypersecretion improves cognitive functions and LTP and promotes neuronal differentiation in adult rats.

Juan Francisco Martín-RodríguezVíctor Darío Ramos-HerreroGloria G ParrasÁlvaro Flores-MartínezAinara Madrazo-AtutxaDavid A CanoAgnès GruartJosé María Delgado-GarcíaAlfonso Leal-CerroRocío Leal-Campanario

Published in: Acta physiologica (Oxford, England) (2019)

Thus, adult-onset hypersecretion of GH/IGF-I improves neurocognitive functions, long-term memories, experimental LTP and neural differentiation, migration and maturation.

Keyphrases

growth hormone
bipolar disorder
cell proliferation
drug induced
brain injury
pi k akt
childhood cancer