Effect of cigarette smoke extract on the intestinal microenvironment of ulcerative colitis tissue.

Aoife CannonNiamh ClarkeFinbar MacCarthyCara DunneDavid KevansNasir MahmudJoanne LysaghtJacintha O'Sullivan

Published in: JGH open : an open access journal of gastroenterology and hepatology (2020)

These data suggest that observed effects of CSE in reducing inflammatory mediators ex vivo are specific to inflamed colonic tissue but are not due to the activation of NF-κB or HIF-1α and are not caused by alterations in subpopulations of T cells in these UC tissues.

Keyphrases

ulcerative colitis
oxidative stress
signaling pathway
stem cells
gene expression
electronic health record
lps induced
endothelial cells
nuclear factor
pi k akt
machine learning