Cognitive function in early-phase schizophrenia-spectrum disorder: IQ subtypes, brain volume and immune markers.

Andrew J WatsonAnnalisa GiordanoJohn SucklingThomas R E BarnesNusrat HusainPeter B JonesCarl R KrynickiStephen M LawrieShôn LewisNaghmeh NikkheslatCarmine M ParianteRachel UpthegroveBill DeakinPaola DazzanEileen M Joyce

Published in: Psychological medicine (2022)

The findings add validity of a neurodevelopmental subtype of schizophrenia identified by comparing estimated premorbid and current IQ and characterised by smaller premorbid brain volume and higher measures of low-grade inflammation (CRP).

Keyphrases

low grade
bipolar disorder
spectrum disorder
high grade
resting state
white matter
functional connectivity
oxidative stress
cerebral ischemia
multiple sclerosis
brain injury
congenital heart disease