Weight change following switch to dolutegravir for HIV treatment in rural Kenya during country roll-out.
Matthew D HickeyErick WafulaSabina M OgachiHellen OjwandoGordon OroriRichard O AdedeLucas Godoy GarrazaMaya L PetersenDiane V HavlirLaura B BalzerJames AyiekoPublished in: Journal of acquired immune deficiency syndromes (1999) (2023)
In contrast to some reports of large weight gain following switch to DTG, we observed small weight increases in women and no weight change in men following DTG switch when on TDF throughout. Weight gain may be attenuated by food insecurity, though was modest even among food-secure.
Keyphrases
- weight gain
- body mass index
- birth weight
- antiretroviral therapy
- weight loss
- hiv infected
- human immunodeficiency virus
- hiv positive
- south africa
- hepatitis c virus
- polycystic ovary syndrome
- magnetic resonance
- hiv aids
- hiv testing
- metabolic syndrome
- type diabetes
- computed tomography
- emergency department
- adipose tissue
- magnetic resonance imaging
- combination therapy
- insulin resistance
- smoking cessation
- electronic health record
- replacement therapy