Detection of benign granular cell tumor of the breast via 18 F-PSMA-PET/CT in a patient with very high-risk prostate cancer: A case report.
Kamyar GhabiliRushi RajyaguruAlexandra De La PlanteKristine L WiddersAlison L ChetlenAngela I ChoeClaudia J KasalesPublished in: SAGE open medical case reports (2024)
Incidental extra-prostatic prostate-specific membrane antigen (PSMA) uptake on initial staging positron emission tomography/computed tomography (PET/CT) scans poses diagnostic challenges, as it can be associated with various benign and malignant lesions. We present the case of a 68-year-old man with very high-risk prostate cancer who was incidentally discovered to have a benign granular cell tumor in the breast initially detected on PSMA-PET/CT. Imaging studies and biopsy were pivotal in the diagnosis, as the tumor's appearance was concerning for breast carcinoma. Recognizing extra-prostatic PSMA uptake in the breast, particularly in patients with prostate cancer, is crucial for guiding appropriate management, accurately interpreting subsequent imaging findings, and assessing radiologic-pathologic correlation.
Keyphrases
- pet ct
- prostate cancer
- positron emission tomography
- radical prostatectomy
- computed tomography
- high resolution
- single cell
- benign prostatic hyperplasia
- cell therapy
- pet imaging
- squamous cell carcinoma
- magnetic resonance imaging
- mass spectrometry
- neoadjuvant chemotherapy
- bone marrow
- quantum dots
- rectal cancer
- label free