Walker-256 tumor alters morphology of intestinal myenteric plexus in rats.
P MaregaE A LibertiJofre Jacob da Silva FreitasK S KietzerPublished in: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society (2018)
This study showed that the Walker-256 tumor induced alterations in the morphology of nitrergic and cholinergic neurons in the myenteric plexus and decreased the upper GI transit with the presence of multiple constrictions in the colon. Therefore, these alterations can interfere on neurotransmission and can be related to the intestinal motility alterations observed in tumor-bearing rats.