Laser-Structured Si and PLGA Inhibit the Neuro2a Differentiation in Mono- and Co-Culture with Glia.
Despoina AngelakiParaskevi KavatzikidouCostas FotakisEmmanuel StratakisAnthi RanellaPublished in: Tissue engineering and regenerative medicine (2022)
Our results highlight the importance of the substrate's topography for the controlled growth and differentiation of the neuronal cells and their further study via protein screening methods could shed light on the factors that lead to limited differentiation; thus, contributing to the long standing request for culture substrates that induce cells to differentiate.