COL1A1, COL4A3, TIMP2 and TGFB1 polymorphisms in cervical insufficiency.

Ana Paula V D AlvesAmanda Brasil de FreitasJosé Eduardo LeviAntonio Gomes de Amorim FilhoLucas A M FrancoMara Sandra HoshidaElizabeth G PatiñoRossana P V FranciscoMario Henrique B Carvalho

Published in: Journal of perinatal medicine (2021)

The findings of the present study corroborate the hypothesis that cervical insufficiency has a genetic component and probably involves genes encoding proteins in the extracellular matrix, in addition to inflammatory processes.

Keyphrases

extracellular matrix
genome wide
oxidative stress
gene expression
copy number
bioinformatics analysis
genome wide analysis