Thymic neuroendocrine tumors in patients with multiple endocrine neoplasia type 1.

Iina YliaskaHeikki TokolaTapani EbelingOuti KuisminOlavi UkkolaMinna L KoivikkoTimo LesonenJussi RimpiläinenTuuli FelinEeva RyhänenSaara MetsoCamilla Schalin-JänttiPasi Salmela

Published in: Endocrine (2022)

In this study, TNETs were observed in one large MEN1 founder pedigree, where an anticipation-like earlier disease onset was observed in the most recent generation. TNET in MEN1 patients is an aggressive disease. The prognosis can be better by systematic screening. We also show that LCNEC can be associated with TNET in MEN1 patients.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
prognostic factors
peritoneal dialysis
neuroendocrine tumors
patient reported