Nickel(0)-Catalyzed Enantioselective [3+2] Annulation of Cyclopropenones and α,β-Unsaturated Ketones/Imines.

Ni0 -catalyzed chemo- and enantioselective [3+2] cycloaddition of cyclopropenones and α,β-unsaturated ketones/imines is described. This reaction integrates C-C bond cleavage of cyclopropenones and enantioselective functionalization by carbonyl/imine group, offering a mild approach to γ-alkenyl butenolides and lactams in excellent enantioselectivity (88-98 % ee) through intermolecular C-C activation.