Unveiling Potential Mechanisms of Spatholobi Caulis against Lung Metastasis of Malignant Tumor by Network Pharmacology and Molecular Docking.

Feiyu Xie Mi-Na Wang Yixin Su Kunmin Xiao Xuelei Chu Sidan Long Lin-Lu Li Xin Zhang Peng Xue Shi-Jie Zhu

Published in: Evidence-based complementary and alternative medicine : eCAM (2022)

Inflammation is the core factor that integrates all these targets, biological process, and signaling pathways, which indicates that SC prevents or reduces lung metastasis mainly by dispelling inflammation.

Keyphrases

molecular docking
oxidative stress
molecular dynamics simulations
signaling pathway
epithelial mesenchymal transition
pi k akt
cell proliferation