Investigation of poly ADP-ribose polymerase inhibitor resistance based on serially collected circulating tumor DNA in patients with BRCA-mutated ovarian cancer.
Yoo-Na KimYeeun ShimJieun SeoZisun ChoiJung-Yun LeeSaeam ShinSang-Wun KimSunghoon KimJong Rak ChoiJung-Yun LeeSeung Tae LeePublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Analysis of serial ctDNAs highlighted multiple acquired resistance mechanisms, providing valuable insights for improving post-progression treatment and survival.