Network Pharmacology Studies on the Molecular Mechanism of Hashimoto's Thyroiditis Treated with Shutiao Qiji Decoction.

Shuang GuoYan LvJunyu ShenRong LiHaipeng LiuYuan FanChunhong Tian

Published in: Combinatorial chemistry & high throughput screening (2023)

It is verified by molecular docking results that Shutiao Qiji Decoction has a potential therapeutic effect on Hashimoto's thyroiditis in the MAPK/TSHR/NOTCH signal pathway, and that the main components, mairin, stigmasterol, poriferast-5-en-3beta-ol, and chryseriol play a role in it. SQD has been shown to have a good therapeutic effect on Hashimoto's thyroiditis.

Keyphrases

molecular docking
molecular dynamics simulations
signaling pathway
cell proliferation
pi k akt
case control
newly diagnosed