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Network Pharmacology Studies on the Molecular Mechanism of Hashimoto's Thyroiditis Treated with Shutiao Qiji Decoction.

Shuang GuoYan LvJunyu ShenRong LiHaipeng LiuYuan FanChunhong Tian
Published in: Combinatorial chemistry & high throughput screening (2023)
It is verified by molecular docking results that Shutiao Qiji Decoction has a potential therapeutic effect on Hashimoto's thyroiditis in the MAPK/TSHR/NOTCH signal pathway, and that the main components, mairin, stigmasterol, poriferast-5-en-3beta-ol, and chryseriol play a role in it. SQD has been shown to have a good therapeutic effect on Hashimoto's thyroiditis.
Keyphrases
  • molecular docking
  • molecular dynamics simulations
  • signaling pathway
  • cell proliferation
  • pi k akt
  • case control
  • newly diagnosed