Highly Stereoselective Synthesis of 1,3-Dienes through an Aryl to Vinyl 1,4-Palladium Migration/Heck Sequence.
Tian-Jiao HuMeng-Yao LiQian ZhaoChen-Guo FengGuo-Qiang LinPublished in: Angewandte Chemie (International ed. in English) (2018)
An efficient aryl to vinyl 1,4-palladium migration/Heck sequence was developed for the stereoselective synthesis of 1,3-dienes. High stereoselectivity was observed not only for 1,3-dienes bearing two similar aryl groups at terminal positions, but also for those with configurations shown to be unfavorable with previous methods.
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