Cellular and molecular atlas of the placenta from a COVID-19 pregnant woman infected at midgestation highlights the defective impacts on foetal health.
Jingsi ChenLili DuFeiyang WangXuan ShaoXiaoyi WangWenzhe YuShilei BiDexiong ChenXingfei PanShanshan ZengLijun HuangYingyu LiangYulian LiRufang ChenFengwu XueXiuying LiShouping WangManli ZhuangMingxing LiuLin LinHao YanFang HeLin YuQingping JiangZhongtang XiongLizi ZhangBin CaoYan-Ling WangDunjin ChenPublished in: Cell proliferation (2022)
These findings illustrate a systematic cellular and molecular signature of placental insufficiency and immune activation at the maternal-foetal interface that may be attributed to SARS-CoV-2 infection at the midgestation stage, which highly suggests the extensive care for maternal and foetal outcomes in pregnant women suffering from COVID-19.
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