Behavior of the Genetic Markers at Screening during the First Trimester of Pregnancy in Euploid Fetuses.

Ximena Carolina Romero Infante Montserrat Uriel Alejandra Gutiérrez María Fernanda Hernández Andres Felipe Hernández Laura Catalina Jiménez Jeadran Nevardo Malagón-Rojas Sara Rincón Franco

Published in: Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia (2022)

Our study demonstrates for the first time the behavior of the biochemical and ultrasonographic markers of chromosomopathy screenings during the first trimester in euploid fetuses in Colombia. Our information is consistent with international reference values. Moreover, we have shown the correlation of different variables with maternal characteristics to determine the variables that could help with development of a screening process during the first trimester with high detection rates.

Keyphrases

gestational age
pregnancy outcomes
preterm birth
genome wide
gene expression
copy number
loop mediated isothermal amplification
dna methylation
body mass index
quantum dots