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Peripheral inflammation in mild cognitive impairment with possible and probable Lewy body disease and Alzheimer's disease.

Eleanor KingJohn Tiernan O'BrienPaul C DonaghyChristopher MorrisNicola BarnettKirsty OlsenCarmen Martin-RuizJohn Paul TaylorAlan J Thomas
Published in: International psychogeriatrics (2019)
There is increased peripheral inflammation in patients with MCI compared to healthy comparison subjects regardless of the MCI subtype. These possible associations with clinical features are consistent with other work showing that inflammation is increased in early disease but require replication. Such findings have importance for timing of putative therapeutic strategies aimed at lowering inflammation.
Keyphrases
  • mild cognitive impairment
  • oxidative stress
  • cognitive decline
  • parkinson disease