Inflammatory markers assessment in an animal model of intracranial hypertension: a randomized trial.
Marcelo Prudente do Espírito SantoCaroline Silvério FariaDavi Jorge Fontoura SollaLeonardo Zumerkorn PipekAlessandro Rodrigo BelonBrasil Ping JengAlmir Ferreira de AndradeManoel Jacobsen TeixeiraWellingson Silva PaivaPublished in: Intensive care medicine experimental (2021)
The serum concentration of cytokines varied in response to intracranial hypertension. The study demonstrated the specific changes in each cytokine after intracranial hypertension and provides key information to guide neuroinflammation clinical research. The proposed experiment was successful as an animal model to the study of neuroinflammation biomarkers.