Molecular Mechanism of Tetramethylpyrazine Ameliorating Neuroexcitotoxicity through Activating the PKA/CREB Signaling Pathway.

Hongxuan Tong Kaili Wang Xiting Wang Tao Lu

Published in: BioMed research international (2022)

This study provided evidence that tetramethylpyrazine can protect against apoptosis caused by neuroexcitotoxicity and the protective mechanism is closely related to the activation of the PKA/CREB signaling pathway.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
cell cycle arrest
induced apoptosis
oxidative stress
cell death