Gut adaptation after gastric bypass in humans reveals metabolically significant shift in fuel metabolism.
Margaret A StefaterCourtney PanciottiHenry A FeldmanWilliam F GourashEleanor ShirleyJohn N HutchinsonLena GolickSang W ParkAnita P CourcoulasNicholas StylopoulosPublished in: Obesity (Silver Spring, Md.) (2022)
These data support a role for a direct effect of intestinal energy metabolism to contribute to the beneficial clinical effects of RYGB, suggesting that related pathways might be potential targets of therapeutic interest for patients with obesity with or without type 2 diabetes.
Keyphrases
- gastric bypass
- roux en y gastric bypass
- weight loss
- type diabetes
- glycemic control
- bariatric surgery
- insulin resistance
- obese patients
- metabolic syndrome
- electronic health record
- weight gain
- cardiovascular disease
- big data
- high fat diet induced
- adipose tissue
- climate change
- human health
- skeletal muscle
- deep learning
- machine learning
- risk assessment