Proteomic analysis of chromophobe renal cell carcinoma and benign renal oncocytoma biopsies reveals shared metabolic dysregulation.
Luis B CarvalhoSusana JorgeHugo López-FernándezCarlos LodeiroRajiv DhirLuis Campos PinheiroMariana MedeirosHugo M SantosJosé-Luis Capelo-MartínezPublished in: Clinical proteomics (2023)
This study underscores the value of integrating high-resolution mass spectrometry protein quantification to effectively characterize and differentiate the proteomic landscapes of solid tumor biopsies diagnosed as chRCC and RO. The insights gained from this research offer valuable information for enhancing our understanding of these conditions and may aid in the development of improved diagnostic and therapeutic strategies.