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Characterization of Aging-Related Genes to Predict Prognosis and Evaluate the Tumor Immune Microenvironment in Malignant Melanoma.

Ni ZengChenrui GuoYajun WangLin LiXi ChenShaoying GaoFeng JiangBilan Cao
Published in: Journal of oncology (2022)
To summarize, we established and validated a model of aging risk based on three aging-related genes that acted as an independent prognostic predictor of overall survival. Besides, it also characterized the immune response in the malignant melanoma microenvironment and could provide a potential indicator of individualized immunotherapy in malignant melanoma.
Keyphrases
  • immune response
  • stem cells
  • dendritic cells
  • toll like receptor