Comparison of the in vitro Anti-Inflammatory Effect of Cannabidiol to Dexamethasone.

Yiming WangXue WangYang YangQianghua QuanTong HuoSimin YangRuijun JuQuan An

Published in: Clinical, cosmetic and investigational dermatology (2022)

These results suggested that CBD and DEX exhibit similar anti-inflammatory effects on LPS-induced RAW264.7 macrophages mainly through suppressing the MAPK and NF-κB signaling pathways, but with different intracellular mechanisms. These findings suggested that CBD may be considered a natural anti-inflammatory agent for protecting skin from immune disorders.

Keyphrases

anti inflammatory
lps induced
signaling pathway
inflammatory response
pi k akt
epithelial mesenchymal transition
oxidative stress
low dose
high dose
cell proliferation