Maternal genetic contribution to pre-pregnancy obesity, gestational weight gain, and gestational diabetes mellitus.

Selvihan BeyselNilnur EyerciMustafa UlubayMustafa CaliskanMuhammed KizilgulMerve HafızoğluErman Cakal

Published in: Diabetology & metabolic syndrome (2019)

The adiposity-related gene FTO is associated with GDM by the effect of FTO on pre-pregnancy obesity. The diabetes-related p.I27L gene is associated with GDM by increasing insulin resistance.

Keyphrases

weight gain
birth weight
insulin resistance
pregnancy outcomes
body mass index
genome wide
type diabetes
copy number
weight loss
preterm birth
metabolic syndrome
pregnant women
adipose tissue
cardiovascular disease
high fat diet induced
high fat diet
genome wide identification
polycystic ovary syndrome
drug induced