Diagnostic performance of melanocytic markers for immunocytochemical evaluation of lymph-node melanoma metastases on cytological samples.

Andrea RonchiFederica Zito MarinoGiorgio ToniFrancesca PagliucaDaniela RussoGiuseppe SignorielloElvira MoscarellaGabriella BrancaccioGiuseppe ArgenzianoRenato FrancoImmacolata Cozzolino

Published in: Journal of clinical pathology (2021)

SOX10 has a 100% detection rate and the most easily interpretable staining pattern compared with other melanocytic markers. Therefore, it is strongly recommended that SOX10 is included in the minimal immunocytochemical panel for the diagnostic evaluation of lymph node FNAC in patients with suspected CM metastasis.

Keyphrases

lymph node
transcription factor
stem cells
neoadjuvant chemotherapy
sentinel lymph node
loop mediated isothermal amplification
flow cytometry
real time pcr
sensitive detection
basal cell carcinoma
locally advanced
ultrasound guided