Breaking the bond between tetranectin and HMGB1 in sepsis.

Cameron W PatersonMandy L FordCraig M Coopersmith

Published in: Science translational medicine (2021)

The interaction between tetranectin and high-mobility group box-1 protein may be manipulated via monoclonal antibodies to improve survival in sepsis (Chen et al. same issue).

Keyphrases

septic shock
acute kidney injury
intensive care unit
binding protein
transcription factor
protein protein
amino acid
free survival