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The haplotype-resolved chromosome pairs of a heterozygous diploid African cassava cultivar reveal novel pan-genome and allele-specific transcriptome features.

Weihong QiYi-Wen LimAndrea PatrignaniPascal SchläpferAnna Bratus-NeuenschwanderSimon GrüterChristelle ChanezNathalie RoddeElisa PratSonia VautrinMargaux-Alison FustierDiogo PratasRalph SchlapbachWilhelm Gruissem
Published in: GigaScience (2022)
The phased and annotated chromosome pairs allow a systematic view of the heterozygous diploid genome organization in cassava with improved accuracy, completeness, and haplotype resolution. They will be a valuable resource for cassava breeding and research. Our study may also provide insights into developing cost-effective and efficient strategies for resolving complex genomes with high resolution, accuracy, and continuity.
Keyphrases
  • genome wide
  • high resolution
  • copy number
  • early onset
  • single cell
  • dna methylation
  • gene expression
  • mass spectrometry
  • single molecule