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Comparative genomics of Leishmania (Mundinia).

Anzhelika ButenkoAlexei Y KostygovJovana SádlováYuliya KleschenkoTomáš BečvářLucie PodešvováDiego H MacedoDavid ŽihalaJulius LukešPaul A BatesPetr VolfFred R OpperdoesVyacheslav Yurchenko
Published in: BMC genomics (2019)
We suggest that adaptation of Mundinia to different vectors and hosts has led to alternative host-parasite relationships and, thereby, made some proteins redundant. Thus, the evolution of genomes in the genus Leishmania and, in particular, in the subgenus Mundinia was mainly shaped by host (or vector) switches.
Keyphrases
  • single cell
  • plasmodium falciparum
  • toxoplasma gondii
  • trypanosoma cruzi