Intraocular Pharmacokinetics and Safety of Subretinal Injection Compared with Intravitreal Application of Conbercept in Vitrectomized Rabbit Eyes.

Teng-Teng YaoXiao-Liang JinYuan YangYi-Xiao WangYa-Li ZhouFang-Lin HeZhao-Yang Wang

Published in: Journal of ophthalmology (2020)

Our study indicates that applying conbercept by subretinal injection can reduce the drug clearance rate and sustain a long maintenance period in ocular tissue, which suggests that subretinal conbercept injection may be a potentially valuable treatment option.

Keyphrases

ultrasound guided
optical coherence tomography
vascular endothelial growth factor
cataract surgery
adverse drug
replacement therapy
smoking cessation