RNA editing is a valuable biomarker for predicting carcinogenesis in ulcerative colitis.

Kazutaka TakahashiKunitoshi ShigeyasuYoshitaka KondoKazuyoshi GotohShuya YanoYuzo UmedaToshihiro InokuchiCaiming XuKazuhiro YoshidaHibiki UmedaToshiaki TakahashiSho TakedaRyuichi YoshidaFuminori TeraishiHiroyuki KishimotoYoshiko MoriKazuhiro NomaYoshinaga OkugawaSakiko HiraokaHiroyuki MichiueHiroshi TazawaOsamu MatsushitaAjay GoelToshiyoshi Fujiwara

Published in: Journal of Crohn's & colitis (2022)

The risk of CAN can be evaluated by assessing ADAR1 expression in the rectum of MES0 UC patients, freeing UC patients from unnecessary colonoscopy and reducing their physical burden. RNA editing may be involved in UC carcinogenesis, and may be used to facilitate the prevention and treatment of CAN in UC.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
crispr cas
chronic kidney disease
peritoneal dialysis
ulcerative colitis
prognostic factors
risk factors
long non coding rna
smoking cessation
replacement therapy
colorectal cancer screening