Affective Behavior in Withdrawal Seizure-Prone and Withdrawal Seizure-Resistant Mice during Long-Term Alcohol Abstinence.
Matthew C HartmannSarah E HolbrookMegan M HaneyJohn C CrabbeAlan M RosenwasserPublished in: Alcoholism, clinical and experimental research (2019)
Selective breeding for acute withdrawal severity has resulted in differences in anxiety-like behavior between WSP and WSR mice. In contrast, however, genes contributing to the severity of acute withdrawal convulsions appear to have little overlap with those predisposing to affective disruption during long-term abstinence.
Keyphrases
- liver failure
- respiratory failure
- bipolar disorder
- high fat diet induced
- smoking cessation
- aortic dissection
- magnetic resonance
- genome wide
- type diabetes
- insulin resistance
- metabolic syndrome
- transcription factor
- adipose tissue
- physical activity
- temporal lobe epilepsy
- depressive symptoms
- contrast enhanced
- alcohol consumption