Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling.

Phillip C SpinosaPatrick C KinnunenBrock A HumphriesGary D LukerKathryn E LukerJennifer J Linderman

Published in: Cellular and molecular bioengineering (2020)

Our data demonstrate that a conserved motif exists for EGFR and CXCR4 signaling and suggest potential clinical utility of the computational model to optimize therapy.

Keyphrases

small cell lung cancer
epidermal growth factor receptor
single cell
tyrosine kinase
cell therapy
transcription factor
cell migration
big data
mesenchymal stem cells
human health
artificial intelligence
smoking cessation