Irinotecan/scFv co-loaded liposomes coaction on tumor cells and CAFs for enhanced colorectal cancer therapy.
Zhaohuan LiChunxi LiuChenglei LiFangqing WangJianhao LiuZengjuan ZhengJingliang WuBo ZhangPublished in: Journal of nanobiotechnology (2021)
In a word, the novel combinational strategy by coaction on both "seeds" and "soils" of the tumor provides a new approach for cancer therapy, and the prepared liposomes could efficiently improve the antitumor effect with promising clinical application prospects.