C/EBPβ Promotes LPS-Induced IL-1β Transcription and Secretion in Alveolar Macrophages via NOD2 Signaling.

Yalan LuoPeng GeHaiyun WenYibo ZhangJin LiuXuanchi DongBowen LanGuixin ZhangQi YangHailong Chen

Published in: Journal of inflammation research (2022)

Ablation of C/EBPβ may attenuate LPS-induced inflammatory damage in AMs by inhibiting the NOD2 receptor signaling pathway. Three natural compounds, N-caffeoyltryptophan, orilotimod, and petasiphenone, may be potential C/EBPβ inhibitors.

Keyphrases

lps induced
signaling pathway
inflammatory response
oxidative stress
pi k akt
epithelial mesenchymal transition
innate immune
transcription factor
induced apoptosis
risk assessment
binding protein
radiofrequency ablation
human health