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Poorly controlled diabetes increases the risk of metastases and castration-resistant prostate cancer in men undergoing radical prostatectomy: Results from the SEARCH database.

Farnoosh Nik-AhdLauren E HowardAdva T EisenbergWilliam J AronsonMartha K TerrisMatthew R CooperbergChristopher L AmlingChristopher J KaneStephen J Freedland
Published in: Cancer (2019)
Among diabetic men undergoing RP, a higher HbA1c value was associated with metastases and CRPC. If validated in larger studies with longer follow-up, future research should test whether better glycemic control improves long-term PC outcomes.
Keyphrases
  • glycemic control
  • radical prostatectomy
  • type diabetes
  • prostate cancer
  • blood glucose
  • weight loss
  • middle aged
  • insulin resistance
  • cardiovascular disease
  • current status
  • adverse drug
  • metabolic syndrome
  • drug induced