Symptom variability over the course of the day in patients with stable COPD in Brazil: a real-world observational study.
Ascédio José RodriguesIrma de GodoyClaudia Henrique da CostaAdalberto Sperb RuninMarcelo Gervilla GregórioAldo Agra de Albuquerque NetoMarina Andrade LimaMonica Corso PereiraSuzana Erico TanniRodrigo Abensur AthanazioElizabeth Jauhar Cardoso BessaFernando César WehrmeisterCristina Bassi LourencoAna Maria Baptista MenezesPublished in: Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia (2019)
Dyspnea was more common in the morning than at night. Having morning or nighttime symptoms was associated with greater daytime symptom severity. Symptom intensity was strongly associated with poor quality of life and with the frequency of exacerbations, although it was weakly associated with airflow limitation.