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Impact of CD34+ cell dose on reduced intensity conditioning regimen haploidentical hematopoietic stem cell transplantation.

María Queralt SalasEshetu G AtenafuMaria Rhida BautistaShruti PremWilson LamArjun Datt LawZeyad-Al ShaibaniDennis Dong Hwan KimFotios V MichelisJeffrey Howard LiptonAuro ViswabandyaJonas MattssonRajat Kumar
Published in: European journal of haematology (2019)
In RIC haplo-SCT, recipients may not benefit from PBSC grafts with a CD34+/kg cell dose higher than 9 × 106 cells/kg, as it can have an adverse impact in post-transplant outcome.
Keyphrases
  • single cell
  • cell therapy
  • induced apoptosis
  • acute myeloid leukemia
  • bone marrow
  • stem cell transplantation
  • high intensity
  • signaling pathway
  • mesenchymal stem cells