Comparison of the Relationship Between Inflammatory Markers and Contrast-Induced Nephropathy in Patients With Acute Coronary Syndrome After Coronary Angiography.
Cagri ZorluCemal KoseogluPublished in: Angiology (2019)
Contrast-induced nephropathy (CIN) is one of the most important complications after invasive cardiovascular procedures. The neutrophil-to-lymphocyte ratio (NLR), mean platelet volume-to-lymphocyte ratio (MPVLR), and platelet-to-lymphocyte ratio (PLR) may be markers of the risk of CIN. We aimed to investigate the association of these indices with the development of CIN in patients with ST-elevation myocardial infarction and non-ST-elevation-acute coronary syndrome who underwent percutaneous coronary intervention. We retrospectively collected the data of patients with ACS after coronary angiography (CA); 564 patients were included (mean age, 62.3 ± 13.0 years; 41.1% female). We compared 62 (10.9%) patients who developed CIN and 502 patients who did not, after CA in terms of NLR, PLR, and MPVLR. Patients who developed CIN had significantly higher MPVLR, NLR, and PLR; the MPVLR (P ≤ .001) was an independent predictor of CIN. NLR, MPVLR, and PLR are simple, cheap, and easily accessible tests that can predict CIN; the MPVLR was the strongest of these predictors.
Keyphrases
- percutaneous coronary intervention
- acute coronary syndrome
- st elevation myocardial infarction
- st segment elevation myocardial infarction
- antiplatelet therapy
- acute myocardial infarction
- magnetic resonance
- coronary artery disease
- high glucose
- coronary artery bypass grafting
- end stage renal disease
- diabetic rats
- newly diagnosed
- drug induced
- heart failure
- peripheral blood
- prognostic factors
- big data
- coronary artery bypass
- electronic health record
- computed tomography
- left ventricular
- atrial fibrillation
- patient reported outcomes
- endothelial cells
- deep learning
- data analysis