Late onset depression: dopaminergic deficit and clinical features of prodromal Parkinson's disease: a cross-sectional study.

Hiba KazmiZuzana WalkerJan BooijFaraan KhanSachit ShahCarole H SudreJoshua E J BuckmanAnette-Eleonore Schrag

Published in: Journal of neurology, neurosurgery, and psychiatry (2020)

LOD is associated with increased rates of motor and non-motor features of PD/DLB and of abnormal 123I-ioflupane SPECTs. These results suggest that patients with LOD should be considered at increased risk of PD/DLB.

Keyphrases

late onset
early onset
depressive symptoms
physical activity
sleep quality