Modulation of hippocampal dopamine and synapse-related proteins by electroacupuncture improves memory deficit caused by sleep deprivation.
Danmei ChenYunpeng ZhangCuiting WangXiaokun WangJimin ShiJihong ZhangWencai GuanBing LiWei FanPublished in: Acupuncture in medicine : journal of the British Medical Acupuncture Society (2020)
In summary, we it appears that EA at GV20 and ST36 may improve SD-induced memory deficits by restoring the quantity of DA in the hippocampus, which is related to activation of CaMK II, synapsin I, and tyrosine hydroxylase. EA may have potential as an alternative therapy for SD and could improve learning and memory deficits among those suffering from sleep deficiency, although this needs verification by prospective clinical studies.
Keyphrases
- cerebral ischemia
- traumatic brain injury
- working memory
- sleep quality
- physical activity
- high glucose
- diabetic rats
- drug induced
- prefrontal cortex
- uric acid
- neuropathic pain
- subarachnoid hemorrhage
- endothelial cells
- oxidative stress
- cognitive impairment
- metabolic syndrome
- blood brain barrier
- spinal cord injury
- replacement therapy
- risk assessment